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March 11, 2010 Volume 31, No. 23

Easing the risk factors

Metabolic health

Exercise helps negative impact of weight regain

With the obesity rate rising for American adults and children, health concerns such as diabetes and cardiovascular disease are a frequent reality. Although obesity itself is a major risk factor for disease, most of the threat may be associated with a cluster of risk factors called the metabolic syndrome (MetS).

Losing weight can improve health and reduce these risk factors, but many people have difficulty keeping the weight off. Now, University of Missouri researchers have found that exercising during weight regain can maintain improvements in metabolic health and disease risk.

In the study, individuals who didn’t exercise during weight regain experienced significant deterioration in metabolic health, while those who exercised maintained improvements in almost all areas.

The MU study, led by Tom Thomas, professor of nutrition and exercise physiology in the College of Human Environmental Sciences, with collaborators from a number of MU departments, is the first to examine the role of exercise in countering the negative effects of weight regain.

“Although many people are successful at losing weight through diet and exercise, the majority of them will relapse and regain the weight,” Thomas says. “The findings of this study indicate that regaining weight is very detrimental; however, exercise can counter those negative effects. The findings support the recommendation to continue exercising after weight loss, even if weight is regained.”

In the study, overweight men and women with measured characteristics of MetS were given a diet and aerobic exercise plan that included supervised exercise five days a week, for 4 to 6 months. After losing weight, participants underwent programmed weight regain and were separated into two groups, one that exercised and one that didn’t.

The non-exercise group experienced rapid deterioration in weight-loss induced benefits to metabolic health. The exercise group maintained improvements in almost all measures.

“It’s clear that the message to lose weight isn’t working because so many people regain weight; a new message is to keep exercising and maintain your weight to reduce disease risk and improve overall health,” Thomas says.